Buy 2–Chlorophenyl cyclopentyl ketone Online / Order Methanone Oil Online

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Buy 2–Chlorophenyl cyclopentyl ketone Online / Order Methanone Oil Online

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2–Chlorophenyl cyclopentyl ketone is used as a reagent in the preparation of bicyclic and polycyclic aromatic hydrocarbons. It acts as a pharmaceutical intermediate and also as an intermediate of ketamine.

Description

2–Chlorophenyl cyclopentyl ketone is used as a reagent in the preparation of bicyclic and polycyclic aromatic hydrocarbons. 2–Chlorophenyl cyclopentyl ketone acts as a pharmaceutical intermediate and also as an intermediate of ketamine.

Chemical Name: 2-Chlorophenyl Cyclopentyl Ketone
Synonyms: (2-Chlorobenzoyl)cyclopentane; Cyclopentyl 2-Chlorophenyl Ketone; Cyclopentyl o-Chlorophenyl Ketone; (2-Chlorophenyl)cyclopentylmethanone;
CAS Number: 6740-85-8
Molecular Formula: C₁₂H₁₃ClO
Appearance: Clear Pale Yellow Oil
Melting Point: N/A
Molecular Weight: 208.68
Storage: Refrigerator
Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Category: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals,

Applications: 2-Chlorophenyl Cyclopentyl Ketone is used as a reagent in the preparation of bicyclic and polycyclic aromatic hydrocarbons. 2-Chlorophenyl cyclopentyl ketone

Step 1: Peroxyacid oxidation (requires isomerization of safrole) or Wacker oxidation (an elegant catalytic oxidation) produces the ketone “PMK” (piperonyl methyl ketone, also known as 3,4-MDP2P, or 3,4-methylenedioxyphenyl-2-propanone.) There are a lot of oxidization reactions available, but in this case we of course want something that will produce the Markovnikov product, with addition occurring at the more substituted end of the alkene. 2-Chlorophenyl cyclopentyl ketone

An initial oxidation to an alcohol followed by a second oxidation step to a ketone is also a possibility. Since safrole and PMK are carefully watched and regulated precursors, the current favorite precursor (typically bought from Chinese chemical manufacturers) is PMK glycidate. 2-Chlorophenyl cyclopentyl ketone

PMK glycidate can reportededly be easily broken down into PMK simply by refluxing it with hydrochloric acid. (But read on about the chemical watch lists!) 2-Chlorophenyl cyclopentyl ketone

Step 2: Reversible imine formation (occurs spontaneously when the ketone is placed in solution with methylamine freebase (not the hydrochloride salt.), 2-Chlorophenyl cyclopentyl ketone

Step 3: Reduction (via hydrides, aluminum-mercury amalgams, or electrical cells) or catalytic hydrogenation permanently converts the imine to MDMA. 2-Chlorophenyl cyclopentyl ketone

Since ketones and imines lack a chiral center, they (like a good Buddhist monk) do not project personal desires on the world, so the resulting product is racemic, containing a 50-50 mix of both the stronger S(+) isomer (which releases plenty of serotonin, dopamine and norepinephrine) and the weaker R(-) isomer (which is effectively just a serotonin releaser.) All MDMA sold on the streets appears to be racemic. 2-Chlorophenyl cyclopentyl ketone

ECHA has no data from registration dossiers on the precautionary measures for using this substance.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Additional information

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1 L, 2 L, 5 L, 10 L, 25 L, 50 L

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